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Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (Retinaldehyde dehydrogenase 1)
One of the metabolic fates of 3-deoxyglucosone, a product of protein deglycation and a potent glycating agent, is to be oxidized to 2-keto-3-deoxygluconate, but the enzyme that catalyses this reaction is presently unknown. Starting from human erythrocytes, which are known to convert 3-deoxyglucosone...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1885224/ https://ncbi.nlm.nih.gov/pubmed/17175089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2006.11.005 |
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