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Identification of 3-deoxyglucosone dehydrogenase as aldehyde dehydrogenase 1A1 (Retinaldehyde dehydrogenase 1)

One of the metabolic fates of 3-deoxyglucosone, a product of protein deglycation and a potent glycating agent, is to be oxidized to 2-keto-3-deoxygluconate, but the enzyme that catalyses this reaction is presently unknown. Starting from human erythrocytes, which are known to convert 3-deoxyglucosone...

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Detalhes bibliográficos
Main Authors: Collard, François, Vertommen, Didier, Fortpied, Juliette, Duester, Gregg, Van Schaftingen, Emile
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1885224/
https://ncbi.nlm.nih.gov/pubmed/17175089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biochi.2006.11.005
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