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Tumor suppression by cell competition through regulation of the Hippo pathway

Homeostatic mechanisms can eliminate abnormal cells to prevent diseases such as cancer. However, the underlying mechanisms of this surveillance are poorly understood. Here we investigated how clones of cells mutant for the neoplastic tumor suppressor gene scribble (scrib) are eliminated from Drosoph...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Chen, Chiao-Lin, Schroeder, Molly C., Kango-Singh, Madhuri, Tao, Chunyao, Halder, Georg
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258595/
https://ncbi.nlm.nih.gov/pubmed/22190496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113882109
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