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Tumor suppression by cell competition through regulation of the Hippo pathway

Homeostatic mechanisms can eliminate abnormal cells to prevent diseases such as cancer. However, the underlying mechanisms of this surveillance are poorly understood. Here we investigated how clones of cells mutant for the neoplastic tumor suppressor gene scribble (scrib) are eliminated from Drosoph...

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Hlavní autoři: Chen, Chiao-Lin, Schroeder, Molly C., Kango-Singh, Madhuri, Tao, Chunyao, Halder, Georg
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258595/
https://ncbi.nlm.nih.gov/pubmed/22190496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113882109
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