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Boundaries of Dachsous Cadherin activity modulate the Hippo signaling pathway to induce cell proliferation

The conserved Hippo tumor suppressor pathway is a key signaling pathway that controls organ size in Drosophila. To date a signal transduction cascade from the Cadherin Fat at the plasma membrane into the nucleus has been discovered. However, how the Hippo pathway is regulated by extracellular signal...

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Detalhes bibliográficos
Main Authors: Willecke, Maria, Hamaratoglu, Fisun, Sansores-Garcia, Leticia, Tao, Chunyao, Halder, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2567464/
https://ncbi.nlm.nih.gov/pubmed/18809931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805201105
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