The apical-basal cell polarity determinant Crumbs regulates Hippo signaling in Drosophila

Defects in apical-basal cell polarity and abnormal expression of cell polarity determinants are often associated with cancer in vertebrates. In Drosophila, abnormal expression of apical-basal determinants can cause neoplastic phenotypes, including loss of cell polarity and overproliferation. However...

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Bibliographic Details
Main Authors: Chen, Chiao-Lin, Gajewski, Kathleen M., Hamaratoglu, Fisun, Bossuyt, Wouter, Sansores-Garcia, Leticia, Tao, Chunyao, Halder, Georg
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2936591/
https://ncbi.nlm.nih.gov/pubmed/20798049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1004060107
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