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The Hippo tumor-suppressor pathway regulates apical-domain size in parallel to tissue growth

The Hippo tumor-suppressor pathway controls tissue growth in Drosophila and mammals by regulating cell proliferation and apoptosis. The Hippo pathway includes the Fat cadherin, a transmembrane protein, which acts upstream of several other components that form a kinase cascade that culminates in the...

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Autors principals: Hamaratoglu, Fisun, Gajewski, Kathleen, Sansores-Garcia, Leticia, Morrison, Clayton, Tao, Chunyao, Halder, Georg
Format: Artigo
Idioma:Inglês
Publicat: Company of Biologists 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704875/
https://ncbi.nlm.nih.gov/pubmed/19531584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.046482
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