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Mask is required for the activity of the Hippo pathway effector Yki/YAP
The Drosophila Yorkie (Yki) protein and its mammalian homolog Yes-associated protein (YAP) are potent growth promoters and YAP overexpression is associated with multiple types of cancer [1,2]. Yki and YAP are transcriptional co-activators and function as downstream effectors of the Hippo tumor suppr...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4089957/ https://ncbi.nlm.nih.gov/pubmed/23333314 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.12.033 |
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