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Mask is required for the activity of the Hippo pathway effector Yki/YAP

The Drosophila Yorkie (Yki) protein and its mammalian homolog Yes-associated protein (YAP) are potent growth promoters and YAP overexpression is associated with multiple types of cancer [1,2]. Yki and YAP are transcriptional co-activators and function as downstream effectors of the Hippo tumor suppr...

詳細記述

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書誌詳細
主要な著者: Sansores-Garcia, Leticia, Atkins, Mardelle, Moya, Ivan M., Shahmoradgoli, Maria, Tao, Chunyao, Mills, Gordon B., Halder, Georg
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4089957/
https://ncbi.nlm.nih.gov/pubmed/23333314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2012.12.033
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