Modulation of the Hippo pathway and organ growth by RNA processing proteins

The Hippo tumor-suppressor pathway regulates organ growth, cell proliferation, and stem cell biology. Defects in Hippo signaling and hyperactivation of its downstream effectors—Yorkie (Yki) in Drosophila and YAP/TAZ in mammals—result in progenitor cell expansion and overgrowth of multiple organs and...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Mach, Jana, Atkins, Mardelle, Gajewski, Kathleen M., Mottier-Pavie, Violaine, Sansores-Garcia, Leticia, Xie, Jun, Mills, Robert Andrew, Kowalczyk, Weronika, Van Huffel, Leen, Mills, Gordon B., Halder, Georg
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2018
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196505/
https://ncbi.nlm.nih.gov/pubmed/30257938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807325115
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