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Modulating F-actin organization induces organ growth by affecting the Hippo pathway

The Hippo tumour suppressor pathway is a conserved signalling pathway that controls organ size. The core of the Hpo pathway is a kinase cascade, which in Drosophila involves the Hpo and Warts kinases that negatively regulate the activity of the transcriptional coactivator Yorkie. Although several ad...

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Detalhes bibliográficos
Main Authors: Sansores-Garcia, Leticia, Bossuyt, Wouter, Wada, Ken-Ichi, Yonemura, Shigenobu, Tao, Chunyao, Sasaki, Hiroshi, Halder, Georg
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116287/
https://ncbi.nlm.nih.gov/pubmed/21556047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.157
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