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CDK7 regulates organ size and tumor growth by safeguarding the Hippo pathway effector Yki/Yap/Taz in the nucleus

Hippo signaling controls organ size and tumor progression through a conserved pathway leading to nuclear translocation of the transcriptional effector Yki/Yap/Taz. Most of our understanding of Hippo signaling pertains to its cytoplasmic regulation, but how the pathway is controlled in the nucleus re...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Cho, Yong Suk, Li, Shuang, Wang, Xiaohui, Zhu, Jian, Zhuo, Shu, Han, Yuhong, Yue, Tao, Yang, Yingzi, Jiang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6938674/
https://ncbi.nlm.nih.gov/pubmed/31857346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.333146.119
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