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The YAP and TAZ transcription coactivators: key downstream effectors of the mammalian Hippo pathway

The Hippo signaling pathway was initially defined by genetic studies in Drosophila to regulate tissue growth and organ size [1, 2]. This pathway is highly conserved in mammals and dysregulation of the Hippo pathway has been implicated in human cancer. Although the exact extracellular signal that con...

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Dettagli Bibliografici
Autori principali: Hong, Wanjin, Guan, Kun-Liang
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3459069/
https://ncbi.nlm.nih.gov/pubmed/22659496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2012.05.004
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