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The YAP and TAZ transcription coactivators: key downstream effectors of the mammalian Hippo pathway
The Hippo signaling pathway was initially defined by genetic studies in Drosophila to regulate tissue growth and organ size [1, 2]. This pathway is highly conserved in mammals and dysregulation of the Hippo pathway has been implicated in human cancer. Although the exact extracellular signal that con...
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| 主要な著者: | , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3459069/ https://ncbi.nlm.nih.gov/pubmed/22659496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcdb.2012.05.004 |
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