The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell

The Hippo pathway plays an important role in regulating tissue homeostasis, and its effectors, the transcriptional co-activators Yes-associated protein (YAP) and WW domain–containing transcription regulator 1 (WWTR1 or TAZ), are responsible for mediating the vast majority of its physiological functi...

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Publicado en:J Biol Chem
Autores principales: Plouffe, Steven W., Lin, Kimberly C., Moore, Jerrell L., Tan, Frederick E., Ma, Shenghong, Ye, Zhen, Qiu, Yunjiang, Ren, Bing, Guan, Kun-Liang
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6052207/
https://ncbi.nlm.nih.gov/pubmed/29802201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002715
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