Polycystic kidney disease: a Hippo connection

di Ma, Shenghong, Guan, Kun-Liang
Pubblicato in Genes Dev (2018)

R-2-hydroxyglutarate as the key effector of IDH mutations promoting oncogenesis

di Ye, Dan, Ma, Shenghong, Xiong, Yue, Guan, Kun-Liang
Pubblicazione 2013

The Hippo pathway effector proteins YAP and TAZ have both distinct and overlapping functions in the cell

di Plouffe, Steven W., Lin, Kimberly C., Moore, Jerrell L., Tan, Frederick E., Ma, Shenghong, Ye, Zhen, Qiu, Yunjiang, Ren, Bing, Guan, Kun-Liang
Pubblicato in J Biol Chem (2018)

D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth

di Ma, Shenghong, Jiang, Bowen, Deng, Wanglong, Gu, Zhong-Kai, Wu, Fei-Zhen, Li, Tingting, Xia, Yukun, Yang, Hui, Ye, Dan, Xiong, Yue, Guan, Kun-Liang
Pubblicato in Oncotarget (2015)

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

di Badur, Mehmet G., Muthusamy, Thangaselvam, Parker, Seth J., Ma, Shenghong, McBrayer, Samuel K., Cordes, Thekla, Magana, Jose H., Guan, Kun-Liang, Metallo, Christian M.
Pubblicato in Cell Rep (2018)

Oncogenic R132 IDH1 Mutations Limit NADPH for De Novo Lipogenesis through (D)2-Hydroxyglutarate Production in Fibrosarcoma Cells

di Badur, Mehmet G., Muthusamy, Thangaselvam, Parker, Seth J., Ma, Shenghong, McBrayer, Samuel K., Cordes, Thekla, Magana, Jose H., Guan, Kun-Liang, Metallo, Christian M.
Pubblicato in Cell Rep (2018)

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

di Xiao, Mengtao, Yang, Hui, Xu, Wei, Ma, Shenghong, Lin, Huaipeng, Zhu, Honguang, Liu, Lixia, Liu, Ying, Yang, Chen, Xu, Yanhui, Zhao, Shimin, Ye, Dan, Xiong, Yue, Guan, Kun-Liang
Pubblicazione 2012

Corrigendum: Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

di Xiao, Mengtao, Yang, Hui, Xu, Wei, Ma, Shenghong, Lin, Huaipeng, Zhu, Honguang, Liu, Lixia, Liu, Ying, Yang, Chen, Xu, Yanhui, Zhao, Shimin, Ye, Dan, Xiong, Yue, Guan, Kun-Liang
Pubblicato in Genes Dev (2015)

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation

di Wang, Yiping, Xiao, Mengtao, Chen, Xiufei, Chen, Leilei, Xu, Yanping, Lv, Lei, Wang, Pu, Yang, Hui, Ma, Shenghong, Lin, Huaipeng, Jiao, Bo, Ren, Ruibao, Ye, Dan, Guan, Kun-Liang, Xiong, Yue
Pubblicato in Mol Cell (2015)

L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration

di Ma, Shenghong, Sun, Renqiang, Jiang, Bowen, Gao, Jun, Deng, Wanglong, Liu, Peng, He, Ruoyu, Cui, Jing, Ji, Minbiao, Yi, Wei, Yang, Pengyuan, Wu, Xiaohui, Xiong, Yue, Qiu, Zilong, Ye, Dan, Guan, Kun-Liang
Pubblicato in Mol Cell Biol (2017)