R-2-hydroxyglutarate as the key effector of IDH mutations promoting oncogenesis

Por Ye, Dan, Ma, Shenghong, Xiong, Yue, Guan, Kun-Liang
Publicado em 2013

D-2-hydroxyglutarate is essential for maintaining oncogenic property of mutant IDH-containing cancer cells but dispensable for cell growth

Por Ma, Shenghong, Jiang, Bowen, Deng, Wanglong, Gu, Zhong-Kai, Wu, Fei-Zhen, Li, Tingting, Xia, Yukun, Yang, Hui, Ye, Dan, Xiong, Yue, Guan, Kun-Liang
Publicado no Oncotarget (2015)

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

Por Xiao, Mengtao, Yang, Hui, Xu, Wei, Ma, Shenghong, Lin, Huaipeng, Zhu, Honguang, Liu, Lixia, Liu, Ying, Yang, Chen, Xu, Yanhui, Zhao, Shimin, Ye, Dan, Xiong, Yue, Guan, Kun-Liang
Publicado em 2012

Corrigendum: Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

Por Xiao, Mengtao, Yang, Hui, Xu, Wei, Ma, Shenghong, Lin, Huaipeng, Zhu, Honguang, Liu, Lixia, Liu, Ying, Yang, Chen, Xu, Yanhui, Zhao, Shimin, Ye, Dan, Xiong, Yue, Guan, Kun-Liang
Publicado no Genes Dev (2015)

WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation

Por Wang, Yiping, Xiao, Mengtao, Chen, Xiufei, Chen, Leilei, Xu, Yanping, Lv, Lei, Wang, Pu, Yang, Hui, Ma, Shenghong, Lin, Huaipeng, Jiao, Bo, Ren, Ruibao, Ye, Dan, Guan, Kun-Liang, Xiong, Yue
Publicado no Mol Cell (2015)

L2hgdh Deficiency Accumulates l-2-Hydroxyglutarate with Progressive Leukoencephalopathy and Neurodegeneration

Por Ma, Shenghong, Sun, Renqiang, Jiang, Bowen, Gao, Jun, Deng, Wanglong, Liu, Peng, He, Ruoyu, Cui, Jing, Ji, Minbiao, Yi, Wei, Yang, Pengyuan, Wu, Xiaohui, Xiong, Yue, Qiu, Zilong, Ye, Dan, Guan, Kun-Liang
Publicado no Mol Cell Biol (2017)