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Hippo pathway effectors YAP/TAZ as novel determinants of ferroptosis
Ferroptosis is a novel form of programmed cell death. We found that the ferroptosis sensitivity in renal and ovarian cancers are regulated by cell density through TAZ-EMP1-NOX4 and TAZ-ANGPTL4-NOX2 pathway, respectively. These findings reveal TAZ as a novel genetic determinant of ferroptosis. Trigge...
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| Publicado no: | Mol Cell Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6961671/ https://ncbi.nlm.nih.gov/pubmed/31993503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2019.1699375 |
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