Pro-Invasive Activity of the Hippo Pathway Effectors YAP and TAZ in Cutaneous Melanoma

YAP and its paralog protein TAZ are downstream effectors of the Hippo pathway. Both are amplified in many human cancers and promote cell proliferation and epithelial–mesenchymal transition. Little is known about the status of the Hippo pathway in cutaneous melanoma. We profiled Hippo pathway compone...

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Autors principals: Nallet-Staub, Flore, Marsaud, Véronique, Li, Ling, Gilbert, Cristèle, Dodier, Sophie, Bataille, Véronique, Sudol, Marius, Herlyn, Meenhard, Mauviel, Alain
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3938155/
https://ncbi.nlm.nih.gov/pubmed/23897276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2013.319
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