Cell Density Sensing Alters TGF-β Signaling in a Cell-Type-Specific Manner, Independent from Hippo Pathway Activation

Cell-cell contacts inhibit cell growth and proliferation in part by activating the Hippo pathway that drives the phosphorylation and nuclear exclusion of the transcriptional coactivators YAP and TAZ. Cell density and Hippo signaling have also been reported to block transforming growth factor β (TGF-...

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Publicado no:Dev Cell
Main Authors: Nallet-Staub, Flore, Yin, Xueqian, Gilbert, Cristèle, Marsaud, Véronique, Ben Mimoun, Saber, Javelaud, Delphine, Leof, Edward B., Mauviel, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4437188/
https://ncbi.nlm.nih.gov/pubmed/25758862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.01.011
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