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The TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis

The Hedgehog (Hh) and Transforming Growth Factor-β (TGF-β) signaling pathways represent essential regulators of cell proliferation and differentiation during embryogenesis. Pathway deregulation is a characteristic of various cancers. Recently, evidence for a convergence of these pathways at the leve...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Javelaud, Delphine, Alexaki, Vasileia I., Dennler, Sylviane, Mohammad, Khalid S., Guise, Theresa A., Mauviel, Alain
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165102/
https://ncbi.nlm.nih.gov/pubmed/21862631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-11-1194
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