GLI2-Mediated Melanoma Invasion and Metastasis

BACKGROUND: The transforming growth factor-β (TGF-β) pathway, which has both tumor suppressor and pro-oncogenic activities, is often constitutively active in melanoma and is a marker of poor prognosis. Recently, we identified GLI2, a mediator of the hedgehog pathway, as a transcriptional target of T...

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Main Authors: Alexaki, Vasileia-Ismini, Javelaud, Delphine, Van Kempen, Leon C. L., Mohammad, Khalid S., Dennler, Sylviane, Luciani, Flavie, Hoek, Keith S., Juàrez, Patricia, Goydos, James S., Fournier, Pierrick J., Sibon, Claire, Bertolotto, Corine, Verrecchia, Franck, Saule, Simon, Delmas, Veronique, Ballotti, Robert, Larue, Lionel, Saiag, Philippe, Guise, Theresa A., Mauviel, Alain
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914763/
https://ncbi.nlm.nih.gov/pubmed/20660365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq257
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