GLI2-Mediated Melanoma Invasion and Metastasis

BACKGROUND: The transforming growth factor-β (TGF-β) pathway, which has both tumor suppressor and pro-oncogenic activities, is often constitutively active in melanoma and is a marker of poor prognosis. Recently, we identified GLI2, a mediator of the hedgehog pathway, as a transcriptional target of T...

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Autori principali: Alexaki, Vasileia-Ismini, Javelaud, Delphine, Van Kempen, Leon C. L., Mohammad, Khalid S., Dennler, Sylviane, Luciani, Flavie, Hoek, Keith S., Juàrez, Patricia, Goydos, James S., Fournier, Pierrick J., Sibon, Claire, Bertolotto, Corine, Verrecchia, Franck, Saule, Simon, Delmas, Veronique, Ballotti, Robert, Larue, Lionel, Saiag, Philippe, Guise, Theresa A., Mauviel, Alain
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2914763/
https://ncbi.nlm.nih.gov/pubmed/20660365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djq257
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