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Tumor suppression by cell competition through regulation of the Hippo pathway

Homeostatic mechanisms can eliminate abnormal cells to prevent diseases such as cancer. However, the underlying mechanisms of this surveillance are poorly understood. Here we investigated how clones of cells mutant for the neoplastic tumor suppressor gene scribble (scrib) are eliminated from Drosoph...

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Bibliografische gegevens
Hoofdauteurs: Chen, Chiao-Lin, Schroeder, Molly C., Kango-Singh, Madhuri, Tao, Chunyao, Halder, Georg
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3258595/
https://ncbi.nlm.nih.gov/pubmed/22190496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113882109
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