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A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway
Mutant larvae for the Drosophila gene lethal giant larva (lgl) develop neoplastic tumors in imaginal discs. However, lgl mutant clones do not form tumors when surrounded by wild-type tissue, suggesting the existence of a tumor-suppressing mechanism. We have investigated the tumorigenic potential of...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930466/ https://ncbi.nlm.nih.gov/pubmed/20679206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009376107 |
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