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A tumor-suppressing mechanism in Drosophila involving cell competition and the Hippo pathway
Mutant larvae for the Drosophila gene lethal giant larva (lgl) develop neoplastic tumors in imaginal discs. However, lgl mutant clones do not form tumors when surrounded by wild-type tissue, suggesting the existence of a tumor-suppressing mechanism. We have investigated the tumorigenic potential of...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930466/ https://ncbi.nlm.nih.gov/pubmed/20679206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1009376107 |
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