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Tumor suppression by cell competition through regulation of the Hippo pathway
Homeostatic mechanisms can eliminate abnormal cells to prevent diseases such as cancer. However, the underlying mechanisms of this surveillance are poorly understood. Here we investigated how clones of cells mutant for the neoplastic tumor suppressor gene scribble (scrib) are eliminated from Drosoph...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258595/ https://ncbi.nlm.nih.gov/pubmed/22190496 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113882109 |
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