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TNF Induces Endotoxin Tolerance Mediated by GSK3 in Macrophages
Endotoxin tolerance, a key mechanism for suppressing excessive inflammatory cytokine production and attendant toxicity, is induced by prior exposure of macrophages to TLR ligands. Induction of tolerance by endogenous cytokines has not been investigated. We show that prior exposure to TNF induces a t...
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| Main Authors: | , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2011
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3258532/ https://ncbi.nlm.nih.gov/pubmed/21602809 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2043 |
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