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Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages
Tumor necrosis factor (TNF) is best known for inducing a rapid but transient NF-κB-mediated inflammatory response. We investigated later phases of TNF signaling, after the initial transient induction of inflammatory genes has subsided, in primary human macrophages. TNF signaling induced expression o...
Enregistré dans:
| Publié dans: | Sci Rep |
|---|---|
| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4997257/ https://ncbi.nlm.nih.gov/pubmed/27558590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31959 |
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