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The Late Endosome is Essential for mTORC1 Signaling

The multisubunit mTORC1 complex integrates signals from growth factors and nutrients to regulate protein synthesis, cell growth, and autophagy. To examine how endocytic trafficking might be involved in nutrient regulation of mTORC1, we perturbed specific endocytic trafficking pathways and measured m...

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Bibliografiset tiedot
Päätekijät: Flinn, Rory J., Yan, Ying, Goswami, Sumanta, Parker, Peter J., Backer, Jonathan M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The American Society for Cell Biology 2010
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828969/
https://ncbi.nlm.nih.gov/pubmed/20053679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0756
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