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The Late Endosome is Essential for mTORC1 Signaling

The multisubunit mTORC1 complex integrates signals from growth factors and nutrients to regulate protein synthesis, cell growth, and autophagy. To examine how endocytic trafficking might be involved in nutrient regulation of mTORC1, we perturbed specific endocytic trafficking pathways and measured m...

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Bibliografiska uppgifter
Huvudupphovsmän: Flinn, Rory J., Yan, Ying, Goswami, Sumanta, Parker, Peter J., Backer, Jonathan M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The American Society for Cell Biology 2010
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2828969/
https://ncbi.nlm.nih.gov/pubmed/20053679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-09-0756
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