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Opposing regulation of the late phase TNF response by mTORC1-IL-10 signaling and hypoxia in human macrophages
Tumor necrosis factor (TNF) is best known for inducing a rapid but transient NF-κB-mediated inflammatory response. We investigated later phases of TNF signaling, after the initial transient induction of inflammatory genes has subsided, in primary human macrophages. TNF signaling induced expression o...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4997257/ https://ncbi.nlm.nih.gov/pubmed/27558590 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31959 |
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