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Differential Dependence of Hypoxia-inducible Factors 1α and 2α on mTORC1 and mTORC2
Constitutive expression of hypoxia-inducible factor (HIF) has been implicated in several proliferative disorders. Constitutive expression of HIF1α and HIF2α has been linked to a number of human cancers, especially renal cell carcinoma (RCC), in which HIF2α expression is the more important contributo...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2596400/ https://ncbi.nlm.nih.gov/pubmed/18945681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800170200 |
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