Differential Dependence of Hypoxia-inducible Factors 1α and 2α on mTORC1 and mTORC2

Constitutive expression of hypoxia-inducible factor (HIF) has been implicated in several proliferative disorders. Constitutive expression of HIF1α and HIF2α has been linked to a number of human cancers, especially renal cell carcinoma (RCC), in which HIF2α expression is the more important contributo...

Full description

Saved in:
Bibliographic Details
Main Authors: Toschi, Alfredo, Lee, Evan, Gadir, Noga, Ohh, Michael, Foster, David A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Accelerated Publications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2596400/
https://ncbi.nlm.nih.gov/pubmed/18945681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C800170200
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items