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mTORC1 and mTORC2 differentially promote natural killer cell development

Natural killer (NK) cells are innate lymphoid cells that are essential for innate and adaptive immunity. Mechanistic target of rapamycin (mTOR) is critical for NK cell development; however, the independent roles of mTORC1 or mTORC2 in regulating this process remain unknown. Ncr1(iCre)-mediated delet...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Yang, Chao, Tsaih, Shirng-Wern, Lemke, Angela, Flister, Michael J, Thakar, Monica S, Malarkannan, Subramaniam
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976438/
https://ncbi.nlm.nih.gov/pubmed/29809146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35619
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