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mTORC1 and mTORC2 differentially promote natural killer cell development

Natural killer (NK) cells are innate lymphoid cells that are essential for innate and adaptive immunity. Mechanistic target of rapamycin (mTOR) is critical for NK cell development; however, the independent roles of mTORC1 or mTORC2 in regulating this process remain unknown. Ncr1(iCre)-mediated delet...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Yang, Chao, Tsaih, Shirng-Wern, Lemke, Angela, Flister, Michael J, Thakar, Monica S, Malarkannan, Subramaniam
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5976438/
https://ncbi.nlm.nih.gov/pubmed/29809146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.35619
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