mTORC1 and mTORC2 are differentially engaged in the development of laser-induced CNV

BACKGROUND: The mechanistic target of rapamycin (mTOR) pathway is a potential target to inhibit pathologic processes in choroidal neovascularization. However, the exact role of mTOR signaling in the development of CNV remains obscure. In this study, we assessed the role of mTORC1 and mTORC2 as well...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell Commun Signal
Main Authors: Yang, Jin Young, Madrakhimov, Sanjar Batirovich, Ahn, Dong Hyuck, Chang, Hun Soo, Jung, Sang Joon, Nah, Seung Kwan, Park, Ha Yan, Park, Tae Kwann
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6570852/
https://ncbi.nlm.nih.gov/pubmed/31200728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-019-0380-0
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