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Peripapillary Intravitreal Injection Improves AAV-Mediated Retinal Transduction

The intravitreal (IVT) injection method is a choice when targeting the inner retina for gene therapy. However, the transduction efficiency of adeno-associated virus (AAV) vectors administered by the IVT route is usually low and may be affected by several factors. To improve the transduction efficien...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Madrakhimov, Sanjar Batirovich, Yang, Jin Young, Ahn, Dong Hyuck, Han, Jung Woo, Ha, Tae Ho, Park, Tae Kwann
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7152690/
https://ncbi.nlm.nih.gov/pubmed/32300611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.03.018
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