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TNFα induces sustained signaling and a prolonged and unremitting inflammatory response in synovial fibroblasts
OBJECTIVE: The non resolving character of synovial inflammation in rheumatoid arthritis (RA) is a conundrum. To identify the contribution of fibroblast-like synoviocytes (FLS) to the perpetuation of synovitis, we investigated the molecular mechanisms that govern the TNFα-driven inflammatory program...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3618592/ https://ncbi.nlm.nih.gov/pubmed/23335080 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37853 |
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