Učitavanje...
The IFN signature and STAT1 expression in RA synovial fluid macrophages are induced by TNFα and counter-regulated by synovial fluid microenvironment
OBJECTIVE: Type I IFNs have emerged as potential activators of the IFN signature and elevated STAT1 expression in RA synovium, but mechanisms that induce synovial IFN expression are unknown. Recently, TNFα was shown to induce a delayed IFN response in macrophages. Thus, we tested whether TNFα, class...
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| Glavni autori: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2012
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3449023/ https://ncbi.nlm.nih.gov/pubmed/22614743 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.34544 |
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