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TNF biology, pathogenic mechanisms and emerging therapeutic strategies

TNF is a pleiotropic cytokine with important functions in homeostasis and disease pathogenesis. Recent discoveries have provided insights into TNF biology that introduce new concepts for the development of therapeutics for TNF-mediated diseases. The model of TNF receptor signalling has been extended...

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Detalhes bibliográficos
Publicado no:Nat Rev Rheumatol
Main Authors: Kalliolias, George D., Ivashkiv, Lionel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4809675/
https://ncbi.nlm.nih.gov/pubmed/26656660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2015.169
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