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TNF biology, pathogenic mechanisms and emerging therapeutic strategies
TNF is a pleiotropic cytokine with important functions in homeostasis and disease pathogenesis. Recent discoveries have provided insights into TNF biology that introduce new concepts for the development of therapeutics for TNF-mediated diseases. The model of TNF receptor signalling has been extended...
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Publicado no: | Nat Rev Rheumatol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4809675/ https://ncbi.nlm.nih.gov/pubmed/26656660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrrheum.2015.169 |
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