Type I IFNs and TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation

Cross-regulation of Toll-like receptor responses by cytokines is essential for effective host defense, avoidance of toxicity, and homeostasis, but the underlying mechanisms are not well understood. A comprehensive epigenomic approach in human macrophages showed that the proinflammatory cytokines TNF...

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Detaylı Bibliyografya
Yayımlandı:Nat Immunol
Asıl Yazarlar: Park, Sung Ho, Kang, Kyuho, Giannopoulou, Eugenia, Qiao, Yu, Kang, Keunsoo, Kim, Geonho, Park-Min, Kyung-Hyun, Ivashkiv, Lionel B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2017
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605457/
https://ncbi.nlm.nih.gov/pubmed/28825701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3818
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