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Type I IFNs and TNF cooperatively reprogram the macrophage epigenome to promote inflammatory activation
Cross-regulation of Toll-like receptor responses by cytokines is essential for effective host defense, avoidance of toxicity, and homeostasis, but the underlying mechanisms are not well understood. A comprehensive epigenomic approach in human macrophages showed that the proinflammatory cytokines TNF...
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| Yayımlandı: | Nat Immunol |
|---|---|
| Asıl Yazarlar: | , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2017
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5605457/ https://ncbi.nlm.nih.gov/pubmed/28825701 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3818 |
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