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Phospholipase D2 (PLD2) Shortens the Time Required for Myeloid Leukemic Cell Differentiation: MECHANISM OF ACTION
Cell differentiation is compromised in acute leukemias. We report that mammalian target of rapamycin (mTOR) and S6 kinase (S6K) are highly expressed in the undifferentiated promyelomonocytic leukemic HL-60 cell line, whereas PLD2 expression is minimal. The expression ratio of PLD2 to mTOR (or to S6K...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3249091/ https://ncbi.nlm.nih.gov/pubmed/22094461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.259465 |
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