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Phagocyte cell migration is mediated by phospholipases PLD1 and PLD2

We have investigated whether the signaling protein phospholipase D is implicated in leukocyte cell motility. Treating differentiated HL-60 cells with small interfering RNAs (siRNAs), to deplete endogenous expression of the PLD1 isoform, led to an abolishment of basal chemokinesis that could not be r...

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Detalhes bibliográficos
Main Authors: Lehman, Nicholas, Di Fulvio, Mauricio, McCray, Nicholas, Campos, Isabel, Tabatabaian, Farnaz, Gomez-Cambronero, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: © 2006 by The American Society of Hematology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895436/
https://ncbi.nlm.nih.gov/pubmed/16873675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-02-005959
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