Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling

Chronic hypoxia activates transforming growth factor-β (TGF-β) signaling and leads to pulmonary vascular remodeling. Pharmacological activation of peroxisome proliferator-activated receptor-γ (PPAR-γ) has been shown to prevent hypoxia-induced pulmonary hypertension and vascular remodeling in rodent...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Gong, Kaizheng, Xing, Dongqi, Li, Peng, Aksut, Baran, Ambalavanan, Namasivayam, Yang, Qinglin, Nozell, Susan E., Oparil, Suzanne, Chen, Yiu-Fai
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2011
Assuntos:
Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233825/
https://ncbi.nlm.nih.gov/pubmed/21926264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2011
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados