Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling

Chronic hypoxia activates transforming growth factor-β (TGF-β) signaling and leads to pulmonary vascular remodeling. Pharmacological activation of peroxisome proliferator-activated receptor-γ (PPAR-γ) has been shown to prevent hypoxia-induced pulmonary hypertension and vascular remodeling in rodent...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gong, Kaizheng, Xing, Dongqi, Li, Peng, Aksut, Baran, Ambalavanan, Namasivayam, Yang, Qinglin, Nozell, Susan E., Oparil, Suzanne, Chen, Yiu-Fai
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Physiological Society 2011
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233825/
https://ncbi.nlm.nih.gov/pubmed/21926264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00062.2011
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