Hypoxia-induced inhibition of lung development is attenuated by the peroxisome proliferator-activated receptor-γ agonist rosiglitazone

Hypoxia enhances transforming growth factor-β (TGF-β) signaling, inhibiting alveolar development and causing abnormal pulmonary arterial remodeling in the newborn lung. We hypothesized that, during chronic hypoxia, reduced peroxisome proliferator-activated receptor-γ (PPAR-γ) signaling may contribut...

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Hoofdauteurs: Nicola, Teodora, Ambalavanan, Namasivayam, Zhang, Wei, James, Masheika L., Rehan, Virender, Halloran, Brian, Olave, Nelida, Bulger, Arlene, Oparil, Suzanne, Chen, Yiu-Fai
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Physiological Society 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129902/
https://ncbi.nlm.nih.gov/pubmed/21531777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00074.2011
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