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Endothelin-1 Mediates Hypoxia-Induced Increases in Vascular Collagen in the Newborn Mouse Lung
Endothelin-1 (ET-1) mediates hypoxia-mediated pulmonary vascular remodeling (HPVR), and endothelin-A receptor (ET-AR) blockade prevents HPVR in newborn mice. Our objective was to determine postnatal effects of chronic hypoxia and/or ET-AR blockade on lung ET-1, ET-AR, ET-BR, and vascular collagen an...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517238/ https://ncbi.nlm.nih.gov/pubmed/17413856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/pdr.0b013e318045beae |
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