Endothelin-A Receptor Blockade Prevents and Partially Reverses Neonatal Hypoxic Pulmonary Vascular Remodeling

Hypoxia-induced pulmonary vascular remodeling (HPVR) may lead to persistent pulmonary hypertension of the newborn or cor pulmonale. Endothelin-1 (ET-1), via endothelin-A (ET(A)) receptor activation, mediates hypoxic pulmonary vasoconstriction. Our objectives were to develop a newborn mouse model of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: AMBALAVANAN, NAMASIVAYAM, BULGER, ARLENE, MURPHY-ULLRICH, JOANNE, OPARIL, SUZANNE, CHEN, YIU-FAI
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2005
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2517586/
https://ncbi.nlm.nih.gov/pubmed/15774824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/01.PDR.0000159512.55862.69
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