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Transforming growth factor-β regulates endothelin-1 signaling in the newborn mouse lung during hypoxia exposure

We have previously shown that inhibition of transforming growth factor-β (TGF-β) signaling attenuates hypoxia-induced inhibition of alveolar development and abnormal pulmonary vascular remodeling in the newborn mice and that endothelin-A receptor (ETAR) antagonists prevent and reverse the vascular r...

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Autors principals: Olave, Nelida, Nicola, Teodora, Zhang, Wei, Bulger, Arlene, James, Masheika, Oparil, Suzanne, Chen, Yiu-Fai, Ambalavanan, Namasivayam
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362161/
https://ncbi.nlm.nih.gov/pubmed/22287612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00258.2011
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