Transforming growth factor-β signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung

Hypoxia causes abnormal neonatal pulmonary artery remodeling (PAR) and inhibition of alveolar development (IAD). Transforming growth factor (TGF)-β is an important regulator of lung development and repair from injury. We tested the hypothesis that inhibition of TGF-β signaling attenuates hypoxia-ind...

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Main Authors: Ambalavanan, Namasivayam, Nicola, Teodora, Hagood, James, Bulger, Arlene, Serra, Rosa, Murphy-Ullrich, Joanne, Oparil, Suzanne, Chen, Yiu-Fai
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494779/
https://ncbi.nlm.nih.gov/pubmed/18487357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00534.2007
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