Transforming growth factor-β signaling mediates hypoxia-induced pulmonary arterial remodeling and inhibition of alveolar development in newborn mouse lung

Hypoxia causes abnormal neonatal pulmonary artery remodeling (PAR) and inhibition of alveolar development (IAD). Transforming growth factor (TGF)-β is an important regulator of lung development and repair from injury. We tested the hypothesis that inhibition of TGF-β signaling attenuates hypoxia-ind...

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Bibliographic Details
Main Authors: Ambalavanan, Namasivayam, Nicola, Teodora, Hagood, James, Bulger, Arlene, Serra, Rosa, Murphy-Ullrich, Joanne, Oparil, Suzanne, Chen, Yiu-Fai
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2494779/
https://ncbi.nlm.nih.gov/pubmed/18487357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00534.2007
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