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Transforming growth factor-β inhibits myocardial PPARγ expression in pressure overload-induced cardiac fibrosis and remodeling in mice

OBJECTIVES: Pharmacological activation of peroxisome proliferator-activated receptor gamma (PPARγ) has been shown to attenuate pressure overload-induced cardiac fibrosis, suggesting that PPARγ has an antifibrotic effect. This study tested the hypothesis that there is a functional interaction between...

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Detalhes bibliográficos
Main Authors: Gong, Kaizheng, Chen, Yiu-Fai, Li, Peng, Lucas, Jason A., Hage, Fadi G., Yang, Qinglin, Nozell, Susan E., Oparil, Suzanne, Xing, Dongqi
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3325019/
https://ncbi.nlm.nih.gov/pubmed/21836474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0b013e32834a4d03
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