O-GlcNAc Modification of NFκB p65 Inhibits TNF-α-Induced Inflammatory Mediator Expression in Rat Aortic Smooth Muscle Cells

BACKGROUND: We have shown that glucosamine (GlcN) or O-(2-acetamido-2-deoxy-D-glucopyranosylidene)amino-N-phenylcarbamate (PUGNAc) treatment augments O-linked-N-acetylglucosamine (O-GlcNAc) protein modification and attenuates inflammatory mediator expression, leukocyte infiltration and neointima for...

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Detalhes bibliográficos
Main Authors: Xing, Dongqi, Gong, Kaizheng, Feng, Wenguang, Nozell, Susan E., Chen, Yiu-Fai, Chatham, John C., Oparil, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3164132/
https://ncbi.nlm.nih.gov/pubmed/21904602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024021
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