Acute O-GlcNAcylation prevents inflammation-induced vascular dysfunction

Acute increases in cellular protein O-linked N-acetyl-glucosamine (O-GlcNAc) modification (O-GlcNAcylation) have been shown to have protective effects in the heart and vasculature. We hypothesized that d-glucosamine (d-GlcN) and Thiamet-G, two agents that increase protein O-GlcNAcylation via differe...

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Detalhes bibliográficos
Main Authors: Hilgers, Rob H. P., Xing, Dongqi, Gong, Kaizheng, Chen, Yiu-Fai, Chatham, John C., Oparil, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
Assuntos:
Vascular Biology and Microcirculation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468474/
https://ncbi.nlm.nih.gov/pubmed/22777418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.01175.2011
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