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The Sulfur-Linked Analogue of O-GlcNAc (S-GlcNAc) Is an Enzymatically Stable and Reasonable Structural Surrogate for O-GlcNAc at the Peptide and Protein Levels

Synthetic proteins bearing site-specific posttranslational modifications have revolutionized our understanding of their biological functions in vitro and in vivo. One such modification, O-GlcNAcylation, is the dynamic addition of β-N-acetyl glucosamine to the side chains of serine and threonine resi...

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Publicat a:Biochemistry
Autors principals: De Leon, Cesar A, Levine, Paul M., Craven, Timothy W., Pratt, Matthew R.
Format: Artigo
Idioma:Inglês
Publicat: 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5598463/
https://ncbi.nlm.nih.gov/pubmed/28627871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b00268
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