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Analysis of the Functional Contributions of Asn233 in Metallo-β-Lactamase IMP-1
Metallo-β-lactamases, such as IMP-1, are a major global health threat, as they provide for bacterial resistance to a wide range of β-lactam antibiotics, including carbapenems. Understanding the molecular details of the enzymatic process and the sequence requirements for function are essential aids i...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232802/ https://ncbi.nlm.nih.gov/pubmed/21896903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00340-11 |
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