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N-Arylsulfonyl Hydrazones as Inhibitors of IMP-1 Metallo-β-Lactamase
Members of a family of N-arylsulfonyl hydrazones have been identified as novel inhibitors of IMP-1, a metallo-β-lactamase of increasing prevalence. Structure-activity relationship studies have indicated a requirement for bulky aromatic substituents on each side of the sulfonyl hydrazone backbone for...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC127367/ https://ncbi.nlm.nih.gov/pubmed/12121917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.46.8.2450-2457.2002 |
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